This Postdoctoral Research Associate, Department of Basic Medical Sciences (College of Medicine-Phoenix) position is with University of Arizona in Phoenix, AZ.
Establish and maintain cancer 3D organoid lines derived from patient tumor and normal biopsies. Perform molecular and cellular assays to characterize organoid lines. Perform CRISPR/Cas9 editing experiments, including CRISPR screens, to functionally characterize cancer-associated genomic alterations. Perform targeted inhibitor screens to detect therapeutic vulnerabilities in organoid lines. Conduct advanced, multi-disciplinary research in cancer genomics under the direction of the principal investigator, Dr. Halmai. Develop, design, and conduct complex research projects. Formulate research methods, develop research criteria, and perform scientific data collection and analysis using independent judgment. Foster collaborations within the Department and with other units across the University. Present results at laboratory meetings and conferences. Prepare manuscripts for publication in peer-reviewed journals. Participate in grant writing, including generating preliminary data, submitting grant applications, and preparing progress reports. Develop and implement protocols as dictated by experimental results. Assist with supervision of laboratory staff. Contribute to daily lab operations. Knowledge, Skills, and Abilities (KSAs): Excellent laboratory and analytical skills and commitment to scientific excellence and innovation. Knowledge of statistics and data analysis and interpretation. Ability to conduct research independently and within a team. Ability to communicate professionally in a clear, concise manner orally and in writing. Knowledge of grant writing and manuscript preparation. Proficiency with imaging or data analysis software.